BDBM50200737 5-(4-((dimethylamino)methyl)phenethyl)-N-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide::CHEMBL217605

SMILES CN(C)Cc1ccc(CCN2CCn3nc(cc3C2=O)C(=O)Nc2ccc(F)cc2)cc1

InChI Key InChIKey=XNTYBRAFFZQBDC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200737   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200737(5-(4-((dimethylamino)methyl)phenethyl)-N-(4-fluoro...)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200737(5-(4-((dimethylamino)methyl)phenethyl)-N-(4-fluoro...)
Affinity DataKi:  82nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed