BDBM50200979 CHEMBL3966155

SMILES Cc1c(Cc2c(CO)nc3c(N)cc(nn23)N2CCOCC2)cccc1C(F)(F)F

InChI Key InChIKey=GCXKULANKFAPOX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200979   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50200979(CHEMBL3966155)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Thr308 after 60 mins by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/31/2018
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50200979(CHEMBL3966155)Copy SMILESCopy InChI

Affinity DataIC50: 52nMAssay Description:Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Ser473 after 60 mins by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/31/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL