BDBM50201040 CHEMBL3935102

SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1

InChI Key InChIKey=VNERMGVCIRNEMM-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201040   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50201040(CHEMBL3935102)
Affinity DataIC50: 17nMAssay Description:Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50201040(CHEMBL3935102)
Affinity DataIC50: 100nMAssay Description:Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50201040(CHEMBL3935102)
Affinity DataIC50: 110nMAssay Description:Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50201040(CHEMBL3935102)
Affinity DataIC50: 300nMAssay Description:Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50201040(CHEMBL3935102)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2018
Entry Details Article
PubMed