BDBM50201382 1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide::CHEMBL241314

SMILES Cc1cc(NC(=O)c2c(NCc3ccncc3)cnn2C)ccc1C(F)(F)F

InChI Key InChIKey=YSSBFDUPJYHIMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201382   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201382(1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201382(1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201382(1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...)
Affinity DataIC50: 560nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed