BDBM50201566 CHEMBL2220483

SMILES NC(=N)c1cc2ccc(OC(=O)c3cccs3)cc2s1

InChI Key InChIKey=OTGQTQBPQCRNRG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201566   

TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201566(CHEMBL2220483)
Affinity DataIC50: 98nMAssay Description:Binding affinity to complement factor D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement C1s subcomponent(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50201566(CHEMBL2220483)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human C1s esterolytic activity using benzyloxycarbonyl-Lys-thiobenzyl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetComplement C1s subcomponent(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50201566(CHEMBL2220483)
Affinity DataIC50: 46nMAssay Description:Inhibition of human serum C1s-mediated lysis of rabbit Ab-sensitized sheep erythrocytes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201566(CHEMBL2220483)
Affinity DataIC50: 96nMAssay Description:Inhibition of human factor D esterolytic activity using benzyloxycarbonyl-Lys-thiobenzyl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed