BDBM50201646 CHEMBL3980696

SMILES CN(c1cc(CO)ccc1Cl)c1nc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)ncc1F

InChI Key InChIKey=AHRSJDAOQNYYAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201646   

TargetSerine/threonine-protein kinase PAK 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201646(CHEMBL3980696)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of PAK1 (unknown origin) by ATP-kinaseGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201646(CHEMBL3980696)
Affinity DataIC50: 480nMAssay Description:Inhibition of PAK1 phosphorylation in human MCF10A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed