BDBM50201726 CHEMBL3897842

SMILES Nc1ccc2CC(Cc2c1)n1nc(-c2cc(F)c3OCCNc3c2)c2c(N)ncnc12

InChI Key InChIKey=ULJLSBKQZMEISX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201726   

TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed