BDBM50202464 CHEMBL3970092

SMILES COc1cc(Nc2ncc(F)c(n2)-c2cc3CN(CCc3o2)S(C)(=O)=O)cc(OC)c1OC

InChI Key InChIKey=KEKSEBMALIJCSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202464   

TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202464(CHEMBL3970092)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202464(CHEMBL3970092)
Affinity DataIC50: 178nMAssay Description:Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed