BDBM50203165 4-trans-((2S)-5-nitroguanidino-2-methylaminopentanoylamino)-L-prolinamide::CHEMBL226448

SMILES CN[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)N[C@H]1CN[C@@H](C1)C(N)=O

InChI Key InChIKey=RMYBKJVFOSIEEJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203165   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203165(4-trans-((2S)-5-nitroguanidino-2-methylaminopentan...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203165(4-trans-((2S)-5-nitroguanidino-2-methylaminopentan...)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203165(4-trans-((2S)-5-nitroguanidino-2-methylaminopentan...)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed