BDBM50203234 CHEMBL3949585

SMILES Cc1nc(N)nc(N)c1C(=O)N1CCN(CC1)c1cc(Cl)ccc1-c1ccccn1

InChI Key InChIKey=MUXOZFYAJYQSMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203234   

TargetDihydrofolate reductase(Human)
Turing Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203234(CHEMBL3949585)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2018
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Turing Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203234(CHEMBL3949585)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2018
Entry Details Article
PubMed