BDBM50204115 CHEMBL245667::N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopropoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES NCCCOCc1ccn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

InChI Key InChIKey=IGODIYJKZLOCRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204115   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204115(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-amino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204115(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-amino...)
Affinity DataIC50: 64nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed