BDBM50204129 (S)-5-((morpholin-2-ylmethoxy)methyl)-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL247127

SMILES C(OCc1ccn2ncnc(Nc3ccc4n(Cc5cccnc5)ncc4c3)c12)[C@@H]1CNCCO1

InChI Key InChIKey=QGTJGYUQPVBUGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204129   

TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204129((S)-5-((morpholin-2-ylmethoxy)methyl)-N-(1-(pyridi...)
Affinity DataIC50: 810nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204129((S)-5-((morpholin-2-ylmethoxy)methyl)-N-(1-(pyridi...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed