BDBM50204139 CHEMBL397122::N-(1-((S)-1-(3-fluorophenyl)ethyl)-1H-indazol-5-yl)-5-(((S)-morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES C[C@@H](c1cccc(F)c1)n1ncc2cc(Nc3ncnn4ccc(COC[C@@H]5CNCCO5)c34)ccc12

InChI Key InChIKey=SGYAQGSCPQGXLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204139   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204139(N-(1-((S)-1-(3-fluorophenyl)ethyl)-1H-indazol-5-yl...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204139(N-(1-((S)-1-(3-fluorophenyl)ethyl)-1H-indazol-5-yl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed