BDBM50204361 CHEMBL3915322

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)CCn1sc2nc(C)cc(C)c2c1=O

InChI Key InChIKey=AKRMHZAKOUMKRI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204361   

TargetProstaglandin G/H synthase 2(Human)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204361(CHEMBL3915322)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204361(CHEMBL3915322)
Affinity DataIC50: 3.03E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204361(CHEMBL3915322)
Affinity DataIC50: 4.97E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204361(CHEMBL3915322)
Affinity DataIC50: 4.97E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed