BDBM50204700 4-(6-(morpholinomethyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)benzamide::CHEMBL390626

SMILES NC(=O)c1ccc(cc1)-c1n[nH]c-2c1Cc1cc(CN3CCOCC3)ccc-21

InChI Key InChIKey=POQDPXKTMXKNPI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204700   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50204700(4-(6-(morpholinomethyl)-1,4-dihydroindeno[1,2-c]py...)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CHK1 assessed as human Cdc25C phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50204700(4-(6-(morpholinomethyl)-1,4-dihydroindeno[1,2-c]py...)
Affinity DataEC50: >5.90E+4nMAssay Description:Antiproliferative activity against human SW620 cells by soft agar assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed