BDBM50204752 CHEMBL3919441

SMILES COc1cc2CC(CC3CCN(Cc4cccc(C)n4)CC3)C(=O)c2cc1OC

InChI Key InChIKey=ZBPKNQIMVQSMLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204752   

TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204752(CHEMBL3919441)
Affinity DataIC50: 73nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204752(CHEMBL3919441)
Affinity DataIC50: 85nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204752(CHEMBL3919441)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204752(CHEMBL3919441)
Affinity DataIC50: 6.57E+4nMAssay Description:Inhibition of human serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed