BDBM50204870 2-[(4-benzyl-piperidin-1-yl)-imino-methyl]-1H-indol-6-ol::CHEMBL220041

SMILES Oc1ccc2cc([nH]c2c1)C(=N)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=BBBUKZLXKVZWHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204870   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204870(2-[(4-benzyl-piperidin-1-yl)-imino-methyl]-1H-indo...)
Affinity DataIC50: 8.5nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204870(2-[(4-benzyl-piperidin-1-yl)-imino-methyl]-1H-indo...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed