BDBM50204888 CHEMBL223695::[4-(3-fluorobenzyl)-piperidine-1-yl]-(6-hydroxy-1H-indole-2-yl)-methanone

SMILES Oc1ccc2cc([nH]c2c1)C(=O)N1CCC(Cc2cccc(F)c2)CC1

InChI Key InChIKey=JFPXKCUDHUXMED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204888   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204888([4-(3-fluorobenzyl)-piperidine-1-yl]-(6-hydroxy-1H...)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204888([4-(3-fluorobenzyl)-piperidine-1-yl]-(6-hydroxy-1H...)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed