BDBM50205255 CHEMBL3890526

SMILES [H][C@@]12CN(Cc3ccc(cc3)-c3ccc4ncnc(Nc5ccc(Oc6ccccc6)c(OC)c5)c4c3)C[C@]1([H])[C@H]2CO

InChI Key InChIKey=WZZXMNBOPNKKSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205255   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50205255(CHEMBL3890526)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GST-fused HER2 (675 to 1255 residues) assessed as phosphotyrosine formation using poly(Glu:Tyr, 4:1) as substrate and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50205255(CHEMBL3890526)
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant human GST-fused EGFR (668 to 1211 residues) assessed as phosphotyrosine formation using poly(Glu:Tyr, 4:1) as substrate and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed