BDBM50205638 CHEMBL3929353

SMILES Cc1cc(C)c(CNC(=O)c2cc(cc3N(CCc23)C2CCOCC2)C#N)c(=O)[nH]1

InChI Key InChIKey=KFCKONLTZDRDDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205638   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205638(CHEMBL3929353)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed