BDBM50205639 CHEMBL3892623

SMILES CC1CN(C2CCOCC2)c2cc(cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c12)-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=AGFJSOIBLBIMSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205639   

TargetHistone-lysine N-methyltransferase EZH1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205639(CHEMBL3892623)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of human EZH1 complex using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205639(CHEMBL3892623)
Affinity DataIC50: 6.98E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205639(CHEMBL3892623)
Affinity DataIC50: 6.98E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed