BDBM50205743 (2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-benzyl-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide::CHEMBL234629

SMILES CCCC[C@H](N)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)N2Cc3ccccc3CC(NC1=O)C2=O)C(N)=O

InChI Key InChIKey=PVCJCCYBNKILDR-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50205743   

TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataIC50: 2.90E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on human MC5R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on human MC4R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on human MC3R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50205743((2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed