BDBM50206484 (2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-3-yl decanoate::CHEMBL400618

SMILES CCCCCCCCCC(=O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C=CBr)c(=O)[nH]c1=O

InChI Key InChIKey=UJLLAVMKZANACG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50206484   

TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dCyd substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dThd substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 8.45E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 1.63E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxyguanosine kinase, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human fibroblast mitochondrial deoxyguanosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed