BDBM50206821 (R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride::CHEMBL535180

SMILES N[C@@H](CC(=O)N1CCCCN1C(=O)c1ccccc1)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=NBEBUKKRRLTYFD-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50206821   

TargetDipeptidyl peptidase 8(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50206821((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...)
Affinity DataKi:  44nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed