BDBM50206860 CHEMBL3974799

SMILES Cc1cc(Nc2cc(C)c(C#N)c(NCCOc3ccccc3Cl)n2)n[nH]1

InChI Key InChIKey=HELPFLHLGBGMOS-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206860   

TargetCytochrome P450 1A2(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206860(CHEMBL3974799)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant Aurora A kinase derived from human Hela cells using kemptide as substrate in presence of [c-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed