BDBM50206967 CHEMBL3942187

SMILES C[C@](O)(c1cncc(c1)-c1nc2ccc(cn2c1C1CC1)C#N)C(F)(F)F

InChI Key InChIKey=GEQUZEFCHLVDGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206967   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Usa

Curated by ChEMBL
LigandPNGBDBM50206967(CHEMBL3942187)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human CYP11B2-CLE9 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Usa

Curated by ChEMBL
LigandPNGBDBM50206967(CHEMBL3942187)
Affinity DataIC50: 220nMAssay Description:Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed