BDBM50207061 CHEMBL3980898

SMILES CO[C@H]1C[C@@H](C1)Oc1cc(F)c(F)c(n1)-c1ccc2O[C@@H](CCC(O)=O)CCc2c1

InChI Key InChIKey=PGPQNVUVHSSUSY-UHFFFAOYSA-N

Data  5 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50207061   

TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at mouse GPR120 expressed in human U2OS cells assessed as beta-arrestin recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50207061(CHEMBL3980898)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse GPR40 assessed as increase in IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details Article
PubMed