BDBM50207121 CHEMBL245648::N-(4-((8-((6,7-dimethoxyisoquinolin-4-yl)methyl)-1-methyl-2,6-dioxo-1,6-dihydro-2H-purin-3(7H)-yl)methyl)phenyl)propane-2-sulfonamide
SMILES COc1cc2cncc(Cc3nc4n(Cc5ccc(NS(=O)(=O)C(C)C)cc5)c(=O)n(C)c(=O)c4[nH]3)c2cc1OC
InChI Key InChIKey=WBRMBHGVOUPISJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50207121
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
