BDBM50207135 8-((6,7-dimethoxyisoquinolin-4-yl)methyl)-3-isobutyl-1,7-dimethyl-1H-purine-2,6(3H,7H)-dione::CHEMBL392752

SMILES COc1cc2cncc(Cc3nc4n(CC(C)C)c(=O)n(C)c(=O)c4n3C)c2cc1OC

InChI Key InChIKey=LUGIPRYODPEONB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207135   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207135(8-((6,7-dimethoxyisoquinolin-4-yl)methyl)-3-isobut...)
Affinity DataIC50: 553nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed