BDBM50207501 CHEMBL387312::N-[4-(3-amino-1-methyl-1H-indazol-4-yl)-phenyl]-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(C)nc(N)c23)c1

InChI Key InChIKey=KXGKWKJLQVNQML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207501   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207501(N-[4-(3-amino-1-methyl-1H-indazol-4-yl)-phenyl]-N'...)
Affinity DataIC50: 8nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207501(N-[4-(3-amino-1-methyl-1H-indazol-4-yl)-phenyl]-N'...)
Affinity DataIC50: 11nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207501(N-[4-(3-amino-1-methyl-1H-indazol-4-yl)-phenyl]-N'...)
Affinity DataIC50: 23nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed