BDBM50207511 1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea::CHEMBL221574

SMILES CCN(CC)CCOn1nc(N)c2c(cccc12)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1

InChI Key InChIKey=OWCONRLOJMQZQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207511   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207511(1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207511(1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 74nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed