BDBM50207523 CHEMBL3982695

SMILES CSc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1

InChI Key InChIKey=RGOMECWMAXEGDR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207523   

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50207523(CHEMBL3982695)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqui5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50207523(CHEMBL3982695)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqui5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50207523(CHEMBL3982695)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqui5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50207523(CHEMBL3982695)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqui5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed