BDBM50208621 CHEMBL3885113

SMILES CSc1ccc(cc1)-n1nnc(n1)-c1ccccc1NC(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=RUMMIJCTDPJGKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208621   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-Universit£T Bonn

Curated by ChEMBL
LigandPNGBDBM50208621(CHEMBL3885113)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in pheophorbide A efflux preincubated for 30 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-Universit£T Bonn

Curated by ChEMBL
LigandPNGBDBM50208621(CHEMBL3885113)
Affinity DataIC50: 221nMAssay Description:Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Rheinische Friedrich-Wilhelms-Universit£T Bonn

Curated by ChEMBL
LigandPNGBDBM50208621(CHEMBL3885113)
Affinity DataIC50: 9.78E+3nMAssay Description:Inhibition of ABCB1 in human A2780/ADR cells assessed as reduction in calcien-AM efflux preincubated for 30 mins followed by calcien-AM addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed