BDBM50208625 CHEMBL3885431

SMILES COc1cccc2c1[nH]c1c2c(cc2cnccc12)C#N

InChI Key InChIKey=UHOPJKMQVDXYAV-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50208625   

LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 28nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 40nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 41nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 41nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 44nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 44nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 180nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 180nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50208625(CHEMBL3885431)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed