BDBM50208628 CHEMBL3885036

SMILES COc1ccc2[nH]c3c(c(C#N)c([nH]c3=O)-c3cccnc3)c2c1

InChI Key InChIKey=SMVHCOBBHAPLPU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208628   

TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 47nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208628(CHEMBL3885036)
Affinity DataIC50: 610nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed