BDBM50208635 CHEMBL3883660

SMILES COc1ccc2c(c1)[nH]c1c2c(cc2cnccc12)C#N

InChI Key InChIKey=UVJQEKJPAVSBTA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50208635   

LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 80nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 34nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 33nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 190nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 190nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 23nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 80nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208635(CHEMBL3883660)
Affinity DataIC50: 33nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed