BDBM50208724 CHEMBL3884250

SMILES COc1cccc2[nH]c3c(c(cc4cnccc34)C#N)c12

InChI Key InChIKey=DSISPBFCWKLZEA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208724   

TargetDual specificity protein kinase CLK1(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 620nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50208724(CHEMBL3884250)
Affinity DataIC50: 850nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed