BDBM50209027 CHEMBL3884038

SMILES OC(=O)CCCNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1

InChI Key InChIKey=XDCOYBQVEVSNNB-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50209027   

TargetSphingosine 1-phosphate receptor 4(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50:  154nMAssay Description:Activation of human S1PR4 expressed in CHO cells assessed as suppression of forskolin-induced intracellular cAMP level measured after 15 mins by ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50:  200nMAssay Description:Agonist activity at recombinant human S1PR4 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50:  370nMAssay Description:Agonist activity at recombinant human S1PR5 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human S1PR2 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human S1PR3 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209027(CHEMBL3884038)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human S1PR1 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed