BDBM50209122 (2,2-dibromo-3-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid::CHEMBL390740

SMILES OC(=O)CC1C(c2ccc(OCCc3ccc4CCCNc4n3)cc2)C1(Br)Br

InChI Key InChIKey=ITGKMDQIQJNXCY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209122   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209122((2,2-dibromo-3-{4-[2-(5,6,7,8-tetrahydro-1,8-napht...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human integrin alpha-v-beta-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209122((2,2-dibromo-3-{4-[2-(5,6,7,8-tetrahydro-1,8-napht...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human integrin alpha-v-beta-3 receptor by solid phase receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209122((2,2-dibromo-3-{4-[2-(5,6,7,8-tetrahydro-1,8-napht...)
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha-v-beta-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209122((2,2-dibromo-3-{4-[2-(5,6,7,8-tetrahydro-1,8-napht...)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of integrin alpha-beta-6 receptor expressed in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed