BDBM50209154 5-methyl-isoxazole-3-carboxylic acid (3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-amide::CHEMBL395695

SMILES Cc1cc(no1)C(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1

InChI Key InChIKey=CJSUPKJJDMWUPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209154   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209154(5-methyl-isoxazole-3-carboxylic acid (3-thiophen-3...)
Affinity DataIC50: 60nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209154(5-methyl-isoxazole-3-carboxylic acid (3-thiophen-3...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Flt1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209154(5-methyl-isoxazole-3-carboxylic acid (3-thiophen-3...)
Affinity DataIC50: 900nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed