BDBM50209217 CHEMBL3885353

SMILES FC(F)(F)c1c(OCc2ccccc2)ccn2c(CC3CC3)nnc12

InChI Key InChIKey=RDNQZFSDTJMHLT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209217   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209217(CHEMBL3885353)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells coexpressing rat glutamate transporter assessed as inhibition of for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209217(CHEMBL3885353)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production by hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMed