BDBM50209294 CHEMBL3884860

SMILES CN(\N=C\c1cnn2ccc(cc12)C#N)S(=O)(=O)c1cc(ccc1OCCN1CCOCC1)[N+]([O-])=O

InChI Key InChIKey=AOXAAEQFLNMCLC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209294   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Auckland

Curated by ChEMBL

LigandBDBM50209294(CHEMBL3884860)Copy SMILESCopy InChI

Affinity DataIC50: 94nMAssay Description:Inhibition of p110delta (unknown origin) using L-alpha phosphatidylinositol as substrate after 1 hr in presence of [gamma33]-ATP by thin layer chroma...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2018
Entry Details Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Auckland

Curated by ChEMBL

LigandBDBM50209294(CHEMBL3884860)Copy SMILESCopy InChI

Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human p110beta/N-terminal His-tagged human p85alpha expressed in baculovirus infected sf cells using L-alpha-phosphatidylin...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL