BDBM50209346 4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide::CHEMBL228926

SMILES CN(C)c1cc2c(Nc3ccc(Oc4ccc(cc4)C(=O)NCC(C)(C)C)c(C)c3)ncnc2cn1

InChI Key InChIKey=NZSOECPTESNCTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209346   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209346(4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-yl...)
Affinity DataIC50: 48nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed