BDBM50209379 (S)-4-(1-hydroxy-3-phenylpropan-2-ylamino)-3-(6-(4-methoxyphenyl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one::CHEMBL440964

SMILES COc1ccc(cc1)-c1cc(C)c2nc([nH]c2c1)-c1c(N[C@H](CO)Cc2ccccc2)cc[nH]c1=O

InChI Key InChIKey=OIEZHHIBUVJWBU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209379   

TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209379((S)-4-(1-hydroxy-3-phenylpropan-2-ylamino)-3-(6-(4...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209379((S)-4-(1-hydroxy-3-phenylpropan-2-ylamino)-3-(6-(4...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209379((S)-4-(1-hydroxy-3-phenylpropan-2-ylamino)-3-(6-(4...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209379((S)-4-(1-hydroxy-3-phenylpropan-2-ylamino)-3-(6-(4...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed