BDBM50209391 4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-methyl-6-(5-methyl-1H-imidazol-2-yl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one::CHEMBL231620

SMILES Cc1c[nH]c(n1)-c1cc(C)c2[nH]c(nc2c1)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O

InChI Key InChIKey=ZTSJUQOBFLZJMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209391   

TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)
Affinity DataIC50: 360nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed