BDBM50209505 CHEMBL244239::N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)ethyl)carbamoyl)phenyl)quinoline-3-carboxamide

SMILES COc1ccc(CCN(C)CCNC(=O)c2ccccc2NC(=O)c2cnc3ccccc3c2)cc1OC

InChI Key InChIKey=LUNFWPKHPVTQAR-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50209505   

TargetCytochrome P450 3A4(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human CYP3A4 expressed in insect microsome using 7-benzyloxy-4-trifluoromethylcoumarin substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human CYP2C9 expressed in insect microsome after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of human CYP2C8 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 7.75E+3nMAssay Description:Inhibition of human CYP2E1 expressed in insect microsome using 7-benzyloxyquinoline substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human CYP2C19 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2E1 expressed in insect microsome after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in insect microsome after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2A6 expressed in insect microsome after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2D6 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209505(N-(2-((2-((3,4-dimethoxyphenethyl)(methyl)amino)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2B6 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed