BDBM50209717 3-(2-hydroxy-1,1-dimethylethyl)-1-(2'-methoxy-4-biphenylmethyl)-1-{2-[1-(4-methylbenzyl)-4-piperidinyl]ethyl}urea::CHEMBL240939

SMILES COc1ccccc1-c1ccc(CN(CCC2CCN(Cc3ccc(C)cc3)CC2)C(=O)NC(C)(C)CO)cc1

InChI Key InChIKey=PYGAQULUJJCELW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209717   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50209717(3-(2-hydroxy-1,1-dimethylethyl)-1-(2'-methoxy-4-bi...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]SNAP from human MCH1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50209717(3-(2-hydroxy-1,1-dimethylethyl)-1-(2'-methoxy-4-bi...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]SNAP-7941 from human MCHR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50209717(3-(2-hydroxy-1,1-dimethylethyl)-1-(2'-methoxy-4-bi...)
Affinity DataKi:  6.68E+3nMAssay Description:Displacement of [125I]Iodoproxyfan from histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed