BDBM50209746 (R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(4-chlorophenylsulfonamido)-3-phenylpropanamide::CHEMBL228030

SMILES CC(C)(C)NCc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=ZNEBNWIAFHHHDT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209746   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209746((R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl...)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHOD cells assessed as effect on DAK-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209746((R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl...)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed