BDBM50209876 (2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide::CHEMBL242131

SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1

InChI Key InChIKey=SLZOGARBQLIHCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209876   

TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209876((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209876((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VEGFR2 in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209876((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...)
Affinity DataIC50: 704nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed