BDBM50210149 CHEMBL3884609

SMILES COC(C1CC1)c1cc(ccc1-c1cc(OC)ccc1F)C1CCc2ccc(cc2O1)[C@@H](CC(O)=O)C1CC1

InChI Key InChIKey=KZKWCIQVXAKUIX-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50210149   

TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  25nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  154nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins in presence of 100% human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  154nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins in presence of 100% human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  531nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins in presence of 100% human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210149(CHEMBL3884609)
Affinity DataEC50:  762nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cells assessed as IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed